Registration Dossier
Registration Dossier
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EC number: 215-209-4 | CAS number: 1313-60-6
Endpoint summary
Administrative data
Description of key information
The exothermic and instantaneous hydrolysis of disodium peroxide (Na2O2 - n°CAS 1313 -60 -6) according the reaction:
Na2O2 + H2O -> 2NaOH + 1/2O2
was confirmed by industrial practice (see section 5.1.2 of the IUCLID dossier). After the reaction, the pH of the solution is > 12. Therefore, disodium peroxide is considered as corrosive and test for sensitisation toxicity are not performed for animal welfare considerations.
Key value for chemical safety assessment
Skin sensitisation
Link to relevant study records
- Endpoint:
- skin sensitisation: in vitro
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the available information indicates that the substance should be classified for respiratory sensitisation or corrosivity
- Endpoint:
- skin sensitisation: in vivo (LLNA)
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the available information indicates that the substance should be classified for respiratory sensitisation or corrosivity
Referenceopen allclose all
Endpoint conclusion
- Endpoint conclusion:
- no study available
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
With the physico-chemical property (sodium hydroxide generation) and the weight of evidence (industrial practise), Na2O2 is considered as corrosive.
Justification for classification or non-classification
With the physico-chemical property (sodium hydroxide generation) and the weight of evidence (industrial practice), disodium peroxide is considered as corrosive and test for sensitisation toxicity are not performed for animal welfare consideration. For this reason, no classification for sensitisation toxicity could be set.
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