Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

According to a 48-hour Immobilisation Test (Limit Test) 48-hour static acute toxicity test with Daphnia magna the test item LEVOTHYROXINE ACID had no toxic effect on Daphnia at aquatic saturation (measured value: 0.32 mg/L; equivalent to 100 mg/L nominal concentration).


According to the 72-h algal growth inhibition test with Raphidocelis subcapitata, the obtained results showed that the test item LEVOTHYROXINE ACID had no toxic effect at aquatic saturation (measured value: 1.04 mg/L; equivalent to 100 mg/L nominal concentration). Accordingly, the 72-h EC50 value was determined to be > 1.04 mg/L (equivalent to > 100 mg/L nominal concentration). The 72-h NOEC was determined to be 1.04 mg/L (equivalent to 100 mg/L nominal concentration). All validity criteria were met.

Additional information