Registration Dossier

Administrative data

Endpoint:
basic toxicokinetics, other
Remarks:
Expert Statement
Type of information:
other: Expert Statement
Adequacy of study:
weight of evidence
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
1-Ethoxy-2,3-difluoro-4-[trans-4-(trans-4-propylcyclohexyl)-cyclohexyl]-benzene
EC Number:
602-941-8
Cas Number:
123560-48-5
Molecular formula:
C23H34F2O
IUPAC Name:
1-Ethoxy-2,3-difluoro-4-[trans-4-(trans-4-propylcyclohexyl)-cyclohexyl]-benzene
Test material form:
solid

Results and discussion

Main ADME resultsopen allclose all
Type:
absorption
Results:
Oral: yes, Dermal: very limited, Inhalative: neglible based on vapour pressure
Type:
distribution
Results:
restricted within the organism, accumulate in lipophilic tissues
Type:
excretion
Results:
most likely via kidney

Applicant's summary and conclusion