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Diss Factsheets

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
The testing laboratory is GLP compliant and the test was carried out according to the principles of GLP. An internal standard operating procedure was followed for the direct scanning calorimetry tests.
Principles of method if other than guideline:
Date 02/10/2017
SOP Reference CTL SOP 320
Test System DSC System 1
Test Filename DSC4028001957A
Crucible Type Gold-lined steel (high pressure, sealed)
Sample Preparation Tested as received
Start Temperature -40°C
Trip Temperature 400°C
Ramp Rate 4 K.min-1
Test Atmosphere Air
Sample Mass 4.7 mg
GLP compliance:
yes
Type of method:
differential scanning calorimetry

Test material

Constituent 1
Reference substance name:
α-Bitter acids, hop, hydrogenated, isomerized
EC Number:
295-619-8
EC Name:
α-Bitter acids, hop, hydrogenated, isomerized
Cas Number:
92113-15-0
IUPAC Name:
α-Bitter acids, hop, hydrogenated, isomerized
Specific details on test material used for the study:
Batch no. EXP 6. Contains 75.81% w/w potassium salt of hop tetrahydroiso-alpha acids.

Results and discussion

Melting / freezing point
Key result
Remarks on result:
not determinable
Remarks:
No firm melting point noted on DSC, as expected for a plant-derived UVCB material

Any other information on results incl. tables

Notes from the test report: “The sample was observed to undergo an endothermic event from -22.0°C (4.2 J.g-1). An exothermic event was then observed to commence from 125.1°C which had a heat of decomposition of -262.4 J.g-1. No further significant energetic events were noted up to 400°C.”

The DSC plot is attached – see “Illustration – picture/graph”

Applicant's summary and conclusion

Conclusions:
Melting point was not distinguishable, as discussed in detail in "Overall Remarks".