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EC number: 205-530-8 | CAS number: 142-26-7
Melting point / freezing point
Administrative data
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 09 March 2016 to 20 July 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- thermal analysis
Test material
- Reference substance name:
- N-2-hydroxyethylacetamide
- EC Number:
- 205-530-8
- EC Name:
- N-2-hydroxyethylacetamide
- Cas Number:
- 142-26-7
- Molecular formula:
- C4H9NO2
- IUPAC Name:
- N-2-hydroxyethylacetamide
- Test material form:
- liquid
Constituent 1
Results and discussion
Melting / freezing point
- Key result
- Melting / freezing pt.:
- 0.5 °C
- Atm. press.:
- 1 atm
- Remarks on result:
- other: Result: Freezing temperature of 0.5 ± 1.0 °C (273.7 ± 1.0 K)
Any other information on results incl. tables
Determination 1:
| Time (s) | Temperature (°C) | Time (s) | Temperature (°C) | Time (s) | Temperature (°C) |
| 0 | 35.0 | 960 | -1.0 | 1920 | 0.5 |
| 30 | 34.0 | 990 | -1.5 | 1950 | 0.5 |
| 60 | 33.0 | 1020 | -2.0 | 1980 | 1.0 |
| 90 | 32.0 | 1050 | -2.5 | 2010 | 1.0 |
| 120 | 31.0 | 1080 | -3.5 | 2040 | 1.0 |
| 150 | 29.0 | 1110 | -4.0 | 2070 | 1.0 |
| 180 | 28.0 | 1140 | -5.0 | 2100 | 1.0 |
| 210 | 26.0 | 1170 | -5.5 | 2130 | 0.0 |
| 240 | 25.0 | 1200 | -6.0 | 2160 | -0.5 |
| 270 | 24.0 | 1230 | -6.5 | 2190 | -0.5 |
| 300 | 23.0 | 1260 | -7.0 | 2220 | -0.5 |
| 330 | 21.5 | 1290 | -7.5 | 2250 | -0.5 |
| 360 | 20.0 | 1320 | -8.0 | 2280 | -0.5 |
| 390 | 19.0 | 1350 | -9.0 | 2310 | -0.5 |
| 420 | 17.5 | 1380 | -9.5 | 2340 | -0.5 |
| 450 | 16.0 | 1410 | -9.5 | 2370 | -0.5 |
| 480 | 15.0 | 1440 | -10.0 | 2400 | -1.0 |
| 510 | 13.5 | 1470 | -10.5 | 2430 | -1.0 |
| 540 | 12.0 | 1500 | -11.0 | 2460 | -1.0v |
| 570 | 11.0 | 1530 | -11.0 | 2490 | -1.5 |
| 600 | 10.0 | 1560 | -11.5 | 2520 | -2.0 |
| 630 | 8.5 | 1590 | -11.5 | 2580 | -2.5 |
| 660 | 7.5 | 1620 | -10.0 | 2610 | -2.5 |
| 690 | 6.0 | 1650 | -8.5 | 2640 | -3.0 |
| 720 | 5.0 | 1680 | -6.0 | 2670 | -3.5 |
| 750 | 4.5 | 1710 | -4.0 | 2700 | -4.0 |
| 780 | 3.5 | 1470 | -2.0 | 2730 | -4.0 |
| 810 | 2.0 | 1770 | -2.0 | 2760 | -4.5 |
| 840 | 1.0 | 1800 | -1.0 | 2790 | -5.0 |
| 870 | 0.5 | 1830 | -0.5 | --- | --- |
| 900 | 0.0 | 1860 | -0.5 | --- | --- |
| 930 | -0.5 | 1890 | 0.5 | --- | --- |
Result: Freezing temperature of 1.0 °C (274.2 K)
Determination 2:
| Time (s) | Temperature (°C) | Time (s) | Temperature (°C) | Time (s) | Temperature (°C) |
| 0 | 35.0 | 630 | 4.0 | 1260 | -9.0 |
| 30 | 34.0 | 660 | 3.5 | 1290 | -4.0 |
| 60 | 33.0 | 690 | 2.0 | 1320 | -3.0 |
| 90 | 32.0 | 720 | 1.5 | 1350 | -2.0 |
| 120 | 30.0 | 750 | 0.0 | 1380 | -0.5 |
| 150 | 29.0 | 780 | -0.5 | 1410 | 0.0 |
| 180 | 27.0 | 810 | -1.5 | 1440 | 0.0 |
| 210 | 25.0 | 840 | -2.0 | 1470 | 0.0 |
| 240 | 22.0 | 870 | -2.5 | 1500 | 0.0 |
| 270 | 20.5 | 900 | -3.0 | 1530 | -0.5 |
| 300 | 18.0 | 930 | -3.5 | 1560 | -0.5 |
| 330 | 16.0 | 960 | -4.0 | 1590 | -0.5 |
| 360 | 14.0 | 990 | -5.0 | 1620 | -1.0 |
| 390 | 12.0 | 1020 | -5.5 | 1650 | -1.5 |
| 420 | 11.0 | 1050 | -6.0 | 1680 | -2.0 |
| 450 | 9.5 | 1080 | -6.5 | 1710 | -3.0 |
| 480 | 9.5 | 1110 | -7.0 | 1470 | -3.5 |
| 510 | 8.0 | 1140 | -8.0 | 1770 | -4.0 |
| 540 | 7.0 | 1170 | -9.0 | 1800 | -4.5 |
| 570 | 6.0 | 1200 | -9.0 | 1830 | -5.0 |
| 600 | 5.0 | 1230 | -9.5 | --- | --- |
Result: Freezing temperature of 0.0 °C (273.2 K)
Applicant's summary and conclusion
- Conclusions:
- The freezing point of the test item has been determined to be 0.5 ± 1.0 °C (273.7 ± 1.0 K).
- Executive summary:
Freezing temperature of 0.5 ± 1.0 °C (273.7 ± 1.0 K) using the crystallizing point method, designed to be compatible with Method A.1 Melting/Freezing Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 102 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
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