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Short-term toxicity to fish

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Key value for chemical safety assessment

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One reliable acute toxicity data point (Klimisch 1, GLP) for a fish species -the zebrafish Danio rerio - has been identified. No effect (mortality) was noted at a nominal test concentration of 100 mg Ba2+/L.

Both the dissolved and total fraction was measured. A white substance was noted in the solution upon addition of BaCl2, most likely caused by the formation of the poorly soluble barium sulfate.

However, at a nominal concentration of 100 mg Ba2+/L, the dissolved and total barium concentrations were 3.5 and 97.5 mg/L, respectively.

Translating the latter value to BaCl2, a 96h-LC50of > 147.8 mg BaCl2/L is derived based on total barium concentration in test solution. Nevertheless, re-calculation of the 96h-LC50 of > 3.5 mg dissolved barium/L results in an LC50of > 5.3 mg BaCl2/L.