Registration Dossier
Registration Dossier
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EC number: 217-298-5 | CAS number: 1805-22-7
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 989
- Report date:
- 1989
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- GLP compliance:
- yes
- Test type:
- standard acute method
Test material
- Reference substance name:
- Nonafluoro(trifluoromethyl)cyclopentane
- EC Number:
- 217-298-5
- EC Name:
- Nonafluoro(trifluoromethyl)cyclopentane
- Cas Number:
- 1805-22-7
- Molecular formula:
- C6F12
- IUPAC Name:
- 1,1,2,2,3,3,4,4,5-Nonafluoro-5-(trifluoromethyl)cyclopentane
- Test material form:
- solid - liquid: suspension
- Details on test material:
- Test materual suspended in arachis oil
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- Males weighed 120-155g, females weighed 132-155g and were approx 5-8 weeks old.
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- arachis oil
- Doses:
- 5000mg/kg bodyweight
- No. of animals per sex per dose:
- 5
- Control animals:
- no
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- discriminating dose
- Effect level:
- > 5 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- None
- Clinical signs:
- No evidence of systemic toxicity was notice.
- Body weight:
- All animals showed expected gain in bodyweight during the study period.
Applicant's summary and conclusion
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information Criteria used for interpretation of results: other: EEC directive 84/449/EEC
- Conclusions:
- Acute oral median lethal dose (LD50) of the test material in the Sprague Dawley strain rat is greater than 5000mg/kg bodyweight.
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