Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The result was obtained from a peer reviewed source.

Data source

Reference
Reference Type:
publication
Title:
The assay of acute vapor toxicity, and the grading and interpretation of results on 96 chemical compounds
Author:
Carpenter CP, Smyth HF Jr, Pozzani UC
Year:
1949
Bibliographic source:
J Ind Hyg Toxicol 31:343-346.

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Unknown.
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
26-24-2
IUPAC Name:
26-24-2
Constituent 2
Reference substance name:
3-Chloro-1,2-propanediol
IUPAC Name:
3-Chloro-1,2-propanediol

Test animals

Species:
rat

Administration / exposure

Route of administration:
inhalation
Duration of exposure:
4 h

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LC50
Effect level:
> 0.397 - < 0.786 mg/L air (nominal)

Applicant's summary and conclusion

Interpretation of results:
toxic
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The substance is toxic by inhalation.