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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Classification & Labelling & PBT assessment

PBT assessment

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Administrative data

PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB

Evidence of the lack of persistency for p-Cumylphenol was concluded from the results of assessment of the chemical structure using the BIOWIN model in the EPISuite program. The BIOWIN results for p-Cumylphenol  are as follows:

• non-linear model (BIOWIN2) prediction: Biodegrades fast (0.72) or

• MITI non-linear model (BIOWIN6) prediction: Does not Biodegrade fast (0.17) and

• ultimate biodegradation timeframe (BIOWIN3) prediction: Weeks-months (2.6)

Based on these results and information available in the European Commission (2003) Technical Guidance Document on Risk Assessment, p-Cumylphenol would not be considered Persistent or Very Persistent.

A reliable QSAR model was used to calculate the bioaccumulation potential of p-Cumylphenol. BCF values were calculated using the BCFBAF v3.01 module embedded within the EPISuite v4.11) computer model. The calculated BCF (regression-based model) was 149 L/kg wet-wt., while the BAF (Arnot-Gobas upper trophic) was 173 L/kg wet-wt. These values are supported by an experimental bioaccumulation study reported on the J-Check website with BCF values ranging from 69 to 190 L/kg. None of these values would classify p-Cumylphenol as Bioaccumulative or Very Bioaccumulative.

Predicted and measured chronic aquatic toxicity tests indicate the substance does not meets the criteria to be regarded as toxic (T). Furthermore p-Cumylphenol is not classified as carcinogenic, germ cell mutagenic, or toxic for reproduction or STOT.