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EC number: - | CAS number: -
All the results suggest that that this UVCB test material has poor absorption characteristics. A very small amount of the test material is absorbed via the GI tract, but that quantity of material undergoes rapid elimination primarily through bile and faeces. Even repeat oral doses of test article do not result in any greater absorption or retention of material at the highest dose (1000 mg/kg/day). Metabolites could not be identified because of the UVCB nature of the test material, and the use of quantitative whole body autoradiography demonstrated that there is was very little distribution and retention in all tissues. All these results demonstrate very low hazard via the oral route up to the tested dose of 1000 mg/kg/day.
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