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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
March 27, 2018 to March 28, 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
European Community (EC), EC No. 761/2009, Part A: Methods for the Determination of Physico-Chemical Properties, Guide-line A.4: “Vapour Pressure”, Official Journal of the European Union No. L220, August 24, 2009
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
Organisation for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals No. 104: “Vapour Pressure”, March 23, 2006
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: isothermal thermogravimetry
Specific details on test material used for the study:
No further details specified in the study report.
Key result
Temp.:
20 °C
Vapour pressure:
0.042 Pa

Weight loss of the test item in the temperature range of 100 °C to 130 °C

Temperature

[°C]

1/T [K]

1000/T [K]

Weight loss

[μg/min]

VT

[g/cm2h]

Log VT

100

100

100

0.00268

0.00268

0.00268

2.68097

2.68097

2.68097

4.722

4.043

4.023

0.000567

0.000485

0.000483

-3.246693

-3.314115

-3.31269

110

110

110

0.00261

0.00261

0.00261

2.61097

2.61097

2.61097

8.900

8.262

7.179

0.001068

0.000991

0.000861

-2.971429

-3.003734

-3.064755

120

120

120

0.00254

0.00254

0.00254

2.54453

2.54453

2.54453

14.830

13.020

12.610

0.001780

0.001562

0.001513

-2.749678

-2.806208

-2.820104

130

130

130

0.00248

0.00248

0.00248

2.48139

2.48139

2.48139

22.350

20.490

17.440

0.002682

0.002459

0.002093

-2.571541

-2.609277

-2.679272

Estimation of VTand PT:

Log VT/at 20 °C

Log PT/at 20 °C

PT/at 20 °C

 

PT[Pa]/at 20 °C

-5.7395259

-1.3740529

0.0422617

 

4.23E-02

 

Conclusions:
The isothermal thermogravimetric effusion method was applied for the de-termination of the vapour pressure of 2-Propanone, reaction products with diphenylamine.
A value of the vapour pressure of the test item was determined using the data obtained between 80 °C and 140 °C. The vapour pressure of the test item was calculated (mean of three determinations) to: 4.23 x 10-2 Pa at 20 °C.
This value however is expected to be overestimated, because it was determined from the molten material.
Executive summary:

The purpose of the study was to determine the vapour pressure of the test item using the isothermal thermogravimetric effusion method. The evaporation rates of the test item at elevated temperatures and ambient pressure were determined by monitoring the weight loss over the time.

 

The isothermal thermogravimetric effusion method was applied for the determination of the vapour pressure of 2-Propanone, reaction products with diphenylamine.

 

A value of the vapour pressure of the test item was determined using the data obtained between 80 °C and 140 °C. The vapour pressure of the test item was calculated (mean of three determinations) to: 4.23 x 10-2Pa at 20 °C.

This value however is expected to be overestimated, because it was determined from the molten material.

Description of key information

The vapour pressure of the test item was calculated (mean of three determinations) to: 4.23 x 10-2 Pa at 20 °C.

Key value for chemical safety assessment

Vapour pressure:
0.042 Pa
at the temperature of:
20 °C

Additional information

The isothermal thermogravimetric effusion method was applied for the determination of the vapour pressure of 2-Propanone, reaction products with diphenylamine. 

A value of the vapour pressure of the test item was determined using the data obtained between 80 °C and 140 °C. The vapour pressure of the test item was calculated (mean of three determinations) to: 4.23 x 10-2 Pa at 20 °C.

This value however is expected to be overestimated, because it was determined from the molten material.