3-((3,4-dicyanophenyl)sulfonyl)-N-(2-hydroxypropyl)propane-1-sulfonamide

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Experiental starting date 4th May 2016. Experimental completion date 20th June 2017. Final report issued 13th October 2017.

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Key result

Water solubility:

ca. 0.214 g/L

Conc. based on:

test mat.

Temp.:

20 °C

pH:

ca. 7.2 - ca. 7.6

Details on results:

The mean concentration was: 0.214 g/L at 20°C. The standard deviation is : 2.65 x10-3 g/L. All the individual results were within +/- 15% of the mean, thus satisfying the criteria specified in the guidelines.

Conclusions:

The water solubility of the test item has been determined to be 0.214 g/L of solution at 20°C +/ - 0.5°C.

Executive summary:

Introduction

The water solubility was determined by using a visual assessment.using a method designed to be compatible with Method A6 water solubility of commission regulation ( EC) no 440/2008 of 30th May 2008 and method 105 of the OECD guidelines for the testing of chemicals 27th July 1995.

The test system consisted of purified water with a resistivity of greater than 15 Mega Ohms.

Conclusion

The water solubility of the test item has been determined to be 0.214g/L at 20°C +/ - 0.5°C.

Key value for chemical safety assessment

Water solubility:

0.214 g/L

at the temperature of:

20 °C