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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Description of key information

Data for 2-(2-(2-ethoxyyethoxy)ethoxy)ethanol:
- Daphnia magna LC50 (48hr) >10000mg/l
- Artemia salina TLm (24hr) >10000mg/l
- QSAR prediction, 48hr EC50 = 14g/L
Data for 3,6,9,12-tetraoxatetradecan-1-ol:
- QSAR prediction, 48hr EC50 = 32g/L

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
10 000 mg/L

Marine water invertebrates

Marine water invertebrates
Effect concentration:
10 000 mg/L

Additional information

No data is available for the UVCB substance itself. A limited number of acute toxicity studies are available in invertebrates for the a major component, 2-(2-(2-ethoxyyethoxy)ethoxy)ethanol ,which show that it is practically non-toxic to daphia and artemia (fresh and salt water species respectively). The LC50 was always in excess of the maximum tested dose. A reliable QSAR predicts that the LC50 of this substance will be 14g/L and that the LC50 of the other major component, 3,6,9,12-tetraoxatetradecan-1-ol, is significantly less toxic (LC50 =32g/L). It therefore seems an acceptable conservative approach to use data from t2-(2-(2-ethoxyethoxy)ethoxy)ethanol in place of absent data for the UVCB substance itself.

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