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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Qualifier:
no guideline required
Principles of method if other than guideline:
No guideline is required for QSAR.
GLP compliance:
no
Key result
Duration:
28 d
Dose descriptor:
NOEC
Effect conc.:
3.95 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: A standard duration of 28 d for chronic studies is assigned.
Conclusions:
QSAR model IRFMN 1.0.0 predicts a NOEC of 3.95 mg/L for daphnia for sodium pyruvate based on 6 similar compounds.
Reliability 2/3

Description of key information

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Dose descriptor:
NOEC
Effect concentration:
3.95 mg/L

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