Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-024-4 | CAS number: 113-24-6
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 960
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- The toxicity of the test item was accessed in mice by subcutaneous injection.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Sodium pyruvate
- EC Number:
- 204-024-4
- EC Name:
- Sodium pyruvate
- Cas Number:
- 113-24-6
- Molecular formula:
- C3H4O3.Na
- IUPAC Name:
- sodium 2-oxopropanoate
- Test material form:
- solid
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- other: subcutaneous injection
- Vehicle:
- not specified
- Details on oral exposure:
- The test item was applied by subcutaneous injection.
- Doses:
- Not specified
- No. of animals per sex per dose:
- Not specified
- Control animals:
- not specified
- Details on study design:
- Not specified
- Statistics:
- Not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 3 533 mg/kg bw
- Based on:
- test mat.
- Mortality:
- Not specified
- Clinical signs:
- other: Not specified
- Gross pathology:
- Not specified
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The acute toxicity of the test item was accessed in mice by subcutaneous injection. The LD50 was determined to be 3533 mg/kg bw.
- Executive summary:
The acute toxicity of the test item was accessed in mice by subcutaneous injection. The LD50 was determined to be 3533 mg/kg bw.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
