Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
August to October 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid
EC Number:
617-180-7
Cas Number:
80875-98-5
Molecular formula:
C9 H15 N O2
IUPAC Name:
(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid
Test material form:
solid: particulate/powder
Details on test material:
Cream to white powder

Results and discussion

Water solubility
Key result
Water solubility:
>= 28.3 - <= 30.4 vol%
Temp.:
20 °C
pH:
ca. 6.1

Applicant's summary and conclusion

Conclusions:
Water Solubility. The water solubility of the test item has been determined to be in the range 28.3 to 30.4% w/w of solution, at 20.0 ± 0.5 ºC, using a flask method designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
Executive summary:

The general physico-chemical properties of 9490 PERHYDROACIDE have been determined. The results are summarized below:

Water Solubility. The water solubility of the test item has been determined to be in the range 28.3 to 30.4% w/w of solution, at 20.0 ± 0.5 ºC, using a flask method designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.