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Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1961
Reliability:
4 (not assignable)
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1961

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Allylidene di(acetate)
EC Number:
212-789-0
EC Name:
Allylidene di(acetate)
Cas Number:
869-29-4
Molecular formula:
C7H10O4
IUPAC Name:
1-(acetyloxy)prop-2-en-1-yl acetate
impurity 1
Chemical structure
Reference substance name:
1-propene-1,3-diol,1,3-diacetate
Cas Number:
1945-91-1
Molecular formula:
C7H10O4
IUPAC Name:
1-propene-1,3-diol,1,3-diacetate
impurity 2
Chemical structure
Reference substance name:
Acetic acid
EC Number:
200-580-7
EC Name:
Acetic acid
Cas Number:
64-19-7
Molecular formula:
C2H4O2
IUPAC Name:
acetic acid
impurity 3
Chemical structure
Reference substance name:
Acetic anhydride
EC Number:
203-564-8
EC Name:
Acetic anhydride
Cas Number:
108-24-7
Molecular formula:
C4H6O3
IUPAC Name:
acetic anhydride
impurity 4
Reference substance name:
Non identified impurities
Molecular formula:
Not applicable
IUPAC Name:
Non identified impurities
Test material form:
liquid

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Key result
Dose descriptor:
LD50
Effect level:
35 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
Category 2 based on GHS criteria
Conclusions:
The oral LD50 of the test substance is 35 mg/kg bw in rats. Therefore it is classified H300 category 2 according to Regulation (EC) No. 1272/2008 and according to the GHS.
Executive summary:

An acute oral toxicity study was performed on PROP-1-ENE-3,3-DIYL ACETATE.

The oral LD50 of the test substance is 35 mg/kg bw in rats.

Therefore it is classified H300 category 2 according to Regulation (EC) No. 1272/2008 and according to the GHS.