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Short-term toxicity to aquatic invertebrates

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Description of key information

Barium fluoride will dissociate in aqueous solution to form barium and fluoride ions. Reliable acute toxicity data for invertebrates are available for barium and fluoride.

A nominal 48h-EC50 of 14.5 mg Ba/L for Daphnia magna is reported by Biesinger and Christensen (1972) corresponding to a 48h-EC50 of 18.5 mg BaF2/L. For fluoride a 48h-EC50 of 26 mg/L was observed in benthic macroinvertebrates corresponding to 120 mg BaF2/L. Comparing acute toxicity levels of Ba and F in freshwater, it can be concluded that the acute toxicity of BaF to aquatic invertebrates is driven by barium and the 48h-EC50 of 18.5 mg BaF2/L for freshwater invertebrates is considered in the freshwater CSA.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
18.5 mg/L

Additional information

For barium fluoride no data on the short-term toxicity to aquatic invertebrates are available. As barium fluoride in water rapidly dissociates into barium and fluoride ions, it is these ions that are expected to be present in the environment and which will therefore be assessed. Reliable acute toxicity data for aquatic invertebrates are available for barium and fluoride ions.


A reliable, nominal 48h-EC50 of 14.5 mg Ba/L has been reported by Biesinger and Christensen (1972) for Daphnia magna. The reported EC50 is based on nominal test concentrations, using the soluble BaCl2 as test substance. The followed test procedure in this 1972 -study was well described and test conditions (e.g., test medium composition) were properly identified. This value corresponds to a 48h-EC50 of 18.5 mg BaF2/L.


The EU RAR for hydrogen fluoride reviews and summarises the available data on short-term toxicity to aquatic invertebrates. The reported EC50 values for Daphnia sp. range from 97-352 mg/L and are based on nominal fluoride concentrations; EC50 values of 10.5 -39 mg/L are reported for marine invertebrates. The most sensitive effect value was found in benthic macroinvertebrates. In this study, fifth instar larvae of five caddisfly species were exposed to sodium fluoride in a static test system for 96 hours. The 48-h EC50 values for fluoride ranged from 26 to 48 mg/L (soft water) corresponding to 120 to 221.5 mg BaF2/L.