Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
eye irritation: in vivo
Remarks:
(Q)SAR Prediction
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification

Data source

Reference
Reference Type:
other: QSAR prediction
Title:
Unnamed
Year:
2017

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
(Q)SAR

Test material

Constituent 1
Chemical structure
Reference substance name:
(17β)-3-Hydroxyestra-1,3,5(10)-trien-17-yl acetate
EC Number:
605-722-5
Cas Number:
1743-60-8
Molecular formula:
C20H26O3
IUPAC Name:
(17β)-3-Hydroxyestra-1,3,5(10)-trien-17-yl acetate
Test material form:
solid: crystalline

Results and discussion

In vivo

Results
Irritation parameter:
other: MMAS
Remarks:
prediction
Score:
15.2
Remarks on result:
no indication of irritation

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met