Registration Dossier

Administrative data

Endpoint:
eye irritation: in vivo
Remarks:
(Q)SAR Prediction
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification

Data source

Reference
Reference Type:
other: QSAR prediction
Title:
Unnamed
Year:
2017

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
(Q)SAR

Test material

Constituent 1
Chemical structure
Reference substance name:
(17β)-3-Hydroxyestra-1,3,5(10)-trien-17-yl acetate
EC Number:
605-722-5
Cas Number:
1743-60-8
Molecular formula:
C20H26O3
IUPAC Name:
(17β)-3-Hydroxyestra-1,3,5(10)-trien-17-yl acetate
Test material form:
solid: crystalline

Results and discussion

In vivo

Results
Irritation parameter:
other: MMAS
Remarks:
prediction
Score:
15.2
Remarks on result:
no indication of irritation

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met