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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to soil microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

EC25 and EC50 (28-day) >100 mg/kg dwt (nominal), nitrate formation rate, soil microorganisms, based on read-across within the Reconsile Siloxane Category.

These values are equivalent to >400 mg/kg dwt when normalised to 2% organic carbon.

Key value for chemical safety assessment

Additional information

No data are available with octaphenylcyclotetrasiloxane (CAS 546-56-5). Data from the structural analogue, phenyl silsesquioxanes (EC 939-487-8), are read across.

28-day EC25 and EC50 values of >100 mg/kg dwt were reported for the effects on the nitrate formation rate of soil microorganisms, based on nominal concentrations. Nitrate formation rates were significantly reduced in all treatment groups compared to the control, which gives a 28-day LOEC of 1.2 mg/kg dwt. However, a dose response relationship was not observed, suggesting the effects to be due to a non-toxic mechanism. The EC25, EC50 and LOEC values are equivalent to >400, >400 and 4.8 mg/kg dwt when normalised to 2% organic carbon.