Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 435-680-1 | CAS number: -
Respiratory sensitisation
Administrative data
- Endpoint:
- respiratory sensitisation, other
- Remarks:
- Experience with the chemical class of the substance and from observations of workers.
- Type of information:
- other: Experience with the chemical class of the substance and from observations of workers.
- Adequacy of study:
- other information
- Study period:
- 2018
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Experience with the chemical class of the substance and from observations of workers.
Data source
Reference
- Reference Type:
- other: Experience at the registrant
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Experience with the chemical class of the substance and from observations of workers.
- GLP compliance:
- no
Test material
- Reference substance name:
- -
- EC Number:
- 435-680-1
- EC Name:
- -
- Cas Number:
- 24701-69-7
- Molecular formula:
- C9H12N2O4S (Hill formula) C9H12N2O4S (CAS formula)
- IUPAC Name:
- (6R,7R)-7-amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- Name: 7-AMCA
Chemical name: 7-Amino-3-methoxy-cefalosporanic acid
Molecular formula: C9H12N2O4S
CAS No.: 24701-69-7
Supplier: Sponsor
Batch No.: 36423006
Certificate of analysis: Available
Purity: 90.1 % on anhydrous basis (HPLC)
Water content: 0.3 %
Solubility: In water 0.1 g/L at 20 °C
In methanol 0.05 g/L
Appearance: Yellowish powder
Conditions of storage: Refrigerator, in the dark. Protected from moisture
Stability: Stable over ca. 6 months under conditions of storage. Stable over several weeks at room temperature
Date of expiry: October 2000
Constituent 1
Test animals
- Species:
- other: Humans
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- Category 1 (respiratory sensitising) based on GHS criteria
- Conclusions:
- Experience with the chemical class of the substance and from observations of workers advises to classify the substance as Resp.Sens. 1.
- Executive summary:
Experience with the chemical class of the substance and from observations of workers advises to classify the substance as Resp.Sens. 1.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
