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Justification for classification or non-classification

In order to evaluate toxicological properties of the substance aluminium vanadium tetraoxide, information on the assessment entities aluminium ions and vanadium ions were considered. For a documentation and justification of that approach, please refer to the separate document attached to section 13, namely Read Across Assessment Report for aluminium vanadium tetraoxide.

The skin sensitisation potential of aluminium vanadium tetraoxide may reasonably be considered to be determined by the bioavailability of the assessment entities aluminium ions and vanadium ions.

According to CLP (1272/2008/EC) classification criteria for sensitisation, classification is not required for aluminium substances. Based on the outcome of sensitisation studies according to Magnusson and Kligman, it can be concluded that tetra-and pentavalent vanadium substances do also not have a sensitisation potential and therefore must not be classified and labelled according to Regulation (EC) 1272/2008. Similarly, classification of aluminium vanadium tetraoxide with respect to a the skin sensitisation potential does not appear to be supported. Thus, according to EC Regulation No. 1272/2008, aluminium vanadium tetraoxide should not be considered to have a skin sensitisation potential, and hence classification or labelling is not required.

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