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Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
between 13 October 2016 and 18 October 2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
This test is only performed to give an impression of the solubility of Dimercaptodiethylsulphide (DMDS) in different organic solvents. It does not claim to determine exact solubility in g/L.
GLP compliance:
no
Other quality assurance:
other: ISO 9001:2008

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2'-thiodiethanethiol
EC Number:
222-671-0
EC Name:
2,2'-thiodiethanethiol
Cas Number:
3570-55-6
Molecular formula:
C4H10S3
IUPAC Name:
2,2'-sulfanediyldiethanethiol
Test material form:
liquid

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Key result
Medium:
other: n-hexane
Solubility:
>= 10 - < 33 g/L
Temp.:
20 °C
Key result
Medium:
acetonitrile
Solubility:
>= 1 000 g/L
Temp.:
21 °C
Key result
Medium:
ethanol
Solubility:
>= 100 - < 200 g/L
Temp.:
20 °C
Test substance stable:
not determined

Applicant's summary and conclusion

Conclusions:
Based on the definition in the European Pharmacopoeia, Dimercaptodiethylsulphide (DMDS) is infinitely soluble in Acetonitrile, readily soluble in Ethanol and sparingly soluble in Hexane.