Registration Dossier
Registration Dossier
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EC number: 910-427-2 | CAS number: -
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
1. HYPOTHESIS FOR THE ANALOGUE APPROACH
The target substance Zinc peroxide and the source substances Zinc oxide, Zinc Chloride, Zinc sulfate, Zinc nitrate are ionic and consist of the Zinc2+ cation and the respective anion.
The read-across is based on the assumption that the zinc cation (as measure for dissolved zinc species) is the determining factor for (eco)toxicity.
For further details, see Justification for read-across attached to IUCLID chapter 13
2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
See Justification for read-across attached to IUCLID chapter 13
3. ANALOGUE APPROACH JUSTIFICATION
See Justification for read-across attached to IUCLID chapter 13
4. DATA MATRIX
See Justification for read-across attached to IUCLID chapter 13 - Reason / purpose for cross-reference:
- read-across: supporting information
- Reason / purpose for cross-reference:
- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
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- read-across source
- Dose descriptor:
- NOEC
- Remarks:
- freshwater
- Effect conc.:
- >= 14 - <= 400 µg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- other: Zn2+
- Basis for effect:
- other: reproduction, mortality, development
- Remarks on result:
- other: duration: 4 d to 35 d depending on test type
- Dose descriptor:
- NOEC
- Remarks:
- marine
- Effect conc.:
- >= 5.6 - <= 900 µg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- other: Zn2+
- Basis for effect:
- other: growth, development, mortality
- Remarks on result:
- other: duration: 4 d to 35 d depending on test type
- Conclusions:
- The NOEC of Zn2+ ranged from 14 to 400 µg/L in freshwater invertebrates and from 5.6 to 900 µg/L in marine invertebrates.
Reference
Description of key information
freshwater:
Data on 13 species available. Species NOECs range between 0.014 and 0.400 mg Zn/l (dissolved concentrations)
Marine:
Data on 26 species available. Species NOECs range between 0.0056 and 0.9 mg Zn/l (dissolved concentrations)
Species NOECs have been put into their respective species sensitivity distributions.
Key value for chemical safety assessment
Additional information
Extensive high quality chronic data were available on 13 different freshwater invertebrate species and 26 marine invertebrate species. These data were all screened for relevancy to the environment under study.
The freshwater species are part of several different taxonomic groups: poriferans (4 species), molluscs (2 species), crustaceans (4 species), rotifers (2 species) and insects (1 species). The sensitivity of these species is equally distributed over the species sensitivity distribution.
The marine species are part of several different taxonomic groups: annelids (4 species), cniderians (1 species), crustaceans (6 species), echinoderms (5 species), molluscs (9 species) and nematods (1 species) .The sensitivity of these species is equally distributed over the species sensitivity distribution.
The invertebrate species NOECs are combined with the other freshwater and marine chronic data in the SSD to give the HC5 from which the respective PNECs are derived.
The available data on hydrogen peroxide show, that Zn2+ is the determining factor for ecotoxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
