Registration Dossier
Registration Dossier
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EC number: 201-796-4 | CAS number: 88-09-5
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1954
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Insufficient information for an assessment of reliability.
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 954
Materials and methods
- Principles of method if other than guideline:
- Not available
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-ethylbutyric acid
- EC Number:
- 201-796-4
- EC Name:
- 2-ethylbutyric acid
- Cas Number:
- 88-09-5
- Molecular formula:
- C6H12O2
- IUPAC Name:
- 2-ethylbutyric acid
- Test material form:
- not specified
Constituent 1
Test animals
- Species:
- rabbit
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 0.52 mL/kg bw
Applicant's summary and conclusion
- Interpretation of results:
- Category 3 based on GHS criteria
- Conclusions:
- A range-finding acute toxicity (dermal) experiment in rabbits obtained an LD50 (lethal dose, 50 %) of 0.52 ml/kg (478 mg/kg). This value falls within the GHS criteria for classification as Acute Toxicity Category 3 via the dermal route.
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