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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1954
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Insufficient information for an assessment of reliability.

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1954

Materials and methods

Principles of method if other than guideline:
Not available
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2-ethylbutyric acid
EC Number:
201-796-4
EC Name:
2-ethylbutyric acid
Cas Number:
88-09-5
Molecular formula:
C6H12O2
IUPAC Name:
2-ethylbutyric acid
Test material form:
not specified

Test animals

Species:
rabbit

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
0.52 mL/kg bw

Applicant's summary and conclusion

Interpretation of results:
Category 3 based on GHS criteria
Conclusions:
A range-finding acute toxicity (dermal) experiment in rabbits obtained an LD50 (lethal dose, 50 %) of 0.52 ml/kg (478 mg/kg). This value falls within the GHS criteria for classification as Acute Toxicity Category 3 via the dermal route.