Registration Dossier

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
4/7/2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The information is derived from a reliable non-GLP in-house study according to OECD TG 117 (HPLC).
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Key result
Type:
log Pow
Partition coefficient:
4.4
Temp.:
25 °C
Remarks on result:
other: pH not provided in the report but is not considered critical
Type:
log Pow
Partition coefficient:
3.5
Temp.:
25 °C
Remarks on result:
other: pH not provided in the study report, but not considered critical
Type:
log Pow
Partition coefficient:
4.7
Temp.:
25 °C
Remarks on result:
other: pH not provided in the study report but not considered critical
Details on results:
The pH is assessed not to be critical based on the absence of acidic and base structural features of PSEUDO LINALYLACET BHT and in its molecular structure. The log Kows cannot be well assigned to the peaks of the key constituents. The log Kow of 4.4 is considered to be a good representative of Pseudo linalyl acetate.
Conclusions:
The partition coefficient of PSEUDO LINALYLACET BHT has resulted in 3 log Kows 3.5, 4.4 and 4.7 at 25°C in a study equivalent to OECD Guideline 117 (HPLC method) in a reliable non-GLP study. The highest log Kow will be taken forward because this log Kow is associated with Myricenyl acetate, being the constituent with the highest concentration in the substance.
Executive summary:

The partition coefficient of  PSEUDO LINALYLACET BHT has been determined as log P = 3.5-4.7 at 25°C in a study equivalent to OECD Guideline 117 (HPLC Method). The highest log Kow will be taken forward because this log Kow is associated with Myricenyl acetate 'mono', being the constituent with the highest concentration in the substance.

Description of key information

The partition coefficient of  PSEUDO LINALYLACET BHT has been determined as log P = 3.5 , 4.4 and 4.7 at 25°C in a study equivalent to OECD Guideline 117 (HPLC Method). These log Kow cannot be well assigned to key constituents, therefore the log Kow of 4.4 is considered a good representative for Pseudo linalyl acetate.

Key value for chemical safety assessment

Log Kow (Log Pow):
4.4
at the temperature of:
25 °C

Additional information