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Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

 N2-Isobutyryl-5’-O-(4,4’-Dimethoxytrityl)-2’-deoxyguanosine is not readily biodegradable.

Additional information

The biodegradation of the test item was assessed in a biodegradation test according to the OECD test guiedline 301 B CO2 Evolution Test and under GLP (Flach 2018). No degradation of N2-Isobutyryl-5’-O-(4,4’-Dimethoxytrityl)-2’-deoxyguanosine was observed during the test duration of 28 days after acidification. Therefore, N2-Isobutyryl-5’-O-(4,4’-Dimethoxytrityl)-2’-deoxyguanosine is not readily biodegradable in the test conditions based on OECD 301 B, CO2 Evolution Test according to the Modified Sturm Test.