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EC number: 947-663-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: Modified flask method based on Method A.6 Water solubility of Commission Regulation (EC) No 440/2008 and Method 105 of the OECD Guidelines for Testing od Chemicals
- GLP compliance:
- yes (incl. QA statement)
- Key result
- Medium:
- n-octanol
- Solubility:
- >= 52.9 - <= 54.9 other: % w/w
- Temp.:
- 20 °C
- Medium:
- n-octanol
- Solubility:
- >= 529 - <= 549 g/L
- Temp.:
- 20 °C
- Remarks on result:
- other: assuming a relative density of ~1 for saturated solution in n-octanol
- Conclusions:
- The solubility of the test item in n-octanol has been determined to be in the range 52.9 to 54.9% w/w at 20.0 ±0.5 °C.
- Executive summary:
The determination of the octanol solubility of the test item was carried out by visual assessment, using a modified flask method based on Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
The standard flask shake method was not applicable to this test item due to the high saturation level. A range of sample concentrations were prepared to visually assess the point at which saturation was reached.
The solubility of the test item in n-octanol has been determined to be in the range 52.9 to 54.9% w/w at 20.0 ±0.5 °C.
Reference
The sample concentrations and observations are shown in the following table:
Sample |
Conc. (% w/w) |
Observations |
1 |
24.9% |
Clear yellow liquid |
2 |
27.4% |
Clear yellow liquid |
3 |
29.1% |
Clear yellow liquid |
4 |
31.0% |
Clear yellow liquid, slightly more viscous than sample 3 |
5 |
33.1% |
Clear yellow liquid, slightly more viscous than sample 4 |
6 |
34.9% |
Clear yellow liquid, slightly more viscous than sample 5 |
7 |
34.8% |
Amber colored liquid |
8 |
37.1% |
Amber colored liquid, slightly more viscous than sample 7 |
9 |
39.0% |
Amber colored liquid, slightly more viscous than sample 8 |
10 |
40.9% |
Amber colored liquid, slightly more viscous than sample 9 |
11 |
42.9% |
Amber colored liquid, slightly more viscous than sample 10 |
12 |
45.0% |
Amber colored liquid, slightly more viscous than sample 11 |
13 |
45.0% |
Amber transparent liquid |
14 |
46.9% |
Amber transparent liquid, slightly more viscous than sample 13 |
15 |
48.9% |
Amber transparent liquid, slightly more viscous than sample 14 |
16 |
50.9% |
Amber transparent liquid, slightly more viscous than sample 15 |
17 |
52.9% |
Amber transparent liquid, slightly more viscous than sample 16 |
18 |
54.9% |
Amber transparent liquid with and amber solid / gel at the bottom |
Description of key information
The determination of the octanol solubility of the test item was carried out by visual assessment, using a modified flask method based on Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
The standard flask shake method was not applicable to this test item due to the high saturation level. A range of sample concentrations were prepared to visually assess the point at which saturation was reached.
The solubility of the test item in n-octanol has been determined to be in the range 52.9 to 54.9% w/w at 20.0 ±0.5 °C.
Key value for chemical safety assessment
Additional information
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