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Description of key information

Calcium is essential to many forms of life and occurs naturally in the environment.  The fatty acid components are either natural or chemically indistinguishable from natural substances. As such, the bioaccumulation of the substances in the calcium salts of monocarboxylic acids C14-C22 category is not considered to be scientifically relevant.

Key value for chemical safety assessment

Additional information

Calcium salts of monocarboxylic acid C14-C22 are not considered to bioaccumulate. Calcium salts of fatty acids are readily biodegradable and the fatty acid components are either natural or chemically indistinguishable from natural substances with a long history of safe use in foods. Calcium is found abundantly in the environment, occurring in hard water. Calcium is also an essential nutrient, commonly found in plants and animals as an essential constituent of leaves, bones, teeth and shells (Lide 2009).

Given the necessity of this element to many forms of life and the prolonged exposure and interactions of humans with calcium in the environment, food and medicines, as well as prolonged exposure to fatty acids C14-C22 in food, the bioaccumulation of the substances in the calcium salts of monocarboxylic acids C14-C22 category is not considered to be scientifically relevant.

In accordance with Annex XI, the bioaccumulation in aquatic species study is scientifically unjustified. Calcium is essential to many forms of life and occurs naturally in the environment. The fatty acid components are either natural or chemically indistinguishable from natural substances. As such, the bioaccumulation of the substances in the calcium salts of monocarboxylic acids C14-C22 category is not considered to be scientifically relevant.

References

Lide DR (editor) (2009) CRC Handbook of Chemistry and Physics (89th edition). CRC Press, Taylor and Francis Group

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