Registration Dossier

Diss Factsheets

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
05 February 2018 to 12 April 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2008
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: OECD Test Guideline 113 Screening Test for Thermal Stability and Stability in Air
Version / remarks:
1981
Deviations:
no
GLP compliance:
no
Type of method:
dynamic method
Remarks:
Vapour-Liquid Equilibrium (VLE). Also tested using Effusion method: Knudsen cell
Key result
Temp.:
20 °C
Vapour pressure:
1.6 Pa
Temp.:
25 °C
Vapour pressure:
3 Pa
Temp.:
50 °C
Vapour pressure:
38.5 Pa

Table 1- Calculated vapour pressure values for the test item

Temperature (⁰C)

Vapour pressure (Pa)

20

1.6

25

3.0

50

38.5

Table 2- Results from dynamic method

Replicate

Temperature (⁰C)

Vapour pressure (Pa)

1

97.8

10.1

2

107.0

20.1

3

119.6

39.9

4

135.6

79.8

5

140.8

100.2

6

150.5

150.2

 

Table 3- Results from the effusion method

Replicate

Temperature (⁰C)

Vapour pressure (Pa)

1

18.2

1.60

2

21.3

2.05

3

24.3

2.12

 

Conclusions:
In conclusion, the vapour pressure of the test item was determined to be 1.6 Pa at 20°C, 3.0 Pa at 25°C and 38.5 at 50°C.
Executive summary:

The vapour pressure of the test item was measured by the dynamic method: Vapour-Liquid Equilibrium (VLE) and by the effusion method: Knudsen cell. The vapour pressure of the test item was determined to be 1.6 Pa at 20°C, 3.0 Pa at 25°C and 38.5 at 50°C by interpolation and extrapolation of the measured vapour pressure curve. This study is considered to be reliable without restriction (Klimisch 1) as it was conducted according to OECD Guideline 104 and EU Method A.4.

Description of key information

In conclusion, the vapour pressure of the test item was determined to be 1.6 Pa at 20°C, 3.0 Pa at 25°C and 38.5 at 50°C.

Key value for chemical safety assessment

Vapour pressure:
1.6 Pa
at the temperature of:
20 °C

Additional information

The vapour pressure of the test item was measured by the dynamic method: Vapour-Liquid Equilibrium (VLE) and by the effusion method: Knudsen cell. The vapour pressure of the test item was determined to be 1.6 Pa at 20°C, 3.0 Pa at 25°C and 38.5 at 50°C by interpolation and extrapolation of the measured vapour pressure curve. This study is considered to be reliable without restriction (Klimisch 1) as it was conducted according to OECD Guideline 104 and EU Method A.4.