Methyl dihydrogen phosphate

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Report date:

2008

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)

Deviations:

no

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

Methyl dihydrogen phosphate

EC Number:

212-379-1

EC Name:

Methyl dihydrogen phosphate

Cas Number:

812-00-0

Molecular formula:

CH5O4P

IUPAC Name:

methyl dihydrogen phosphate

Test material form:

liquid

Sampling and analysis

Analytical monitoring:

no

Test organisms

Test organisms (species):

Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

72 h

Test conditions

pH:

- Intitial pH (0 h) 2.30 to 6.60
- Final pH (72 h) 7.50 to 8.64

Nominal and measured concentrations:

Nominal test concentrations of 56.2, 100.0, 177.8, 316.2, 562.3 and 1000 mg/L

Reference substance (positive control):

yes

Remarks:

3,5-dichlorophenol (1.5 mg/L)

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

> 1 000 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

growth rate

Effect concentrations 2

Duration:

72 h

Dose descriptor:

NOEC

Effect conc.:

1 000 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

growth rate

Applicant's summary and conclusion

Conclusions:

EC50 (72 h) was reported as > 1000 mg/L and the NOEC was reported as 1000 mg/L.

Executive summary:

Investigation of algal growth rate under static conditions gave an EC50 (72 h) value of > 1000 mg/L and the NOEC was reported as 1000 mg/L.