Alcohols, C16-18 and ethoxylated C16-18 , phosphates (20 moles ethoxylation)

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Study period:

From September 18, 2017 to December 05, 2017

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

The study was suspected to be influenced by trapped gas/impurities.

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Version / remarks:

EU Regulation (EC) 440/2008, Annex Part A test A4.

Deviations:

not specified

GLP compliance:

yes

Type of method:

static method

Key result

Test no.:

#1

Temp.:

ca. 20 °C

Vapour pressure:

ca. 4.6 Pa

Remarks on result:

other: Mean of run 1 and run 2

Full test results

Temp / °C	Temp / K	P / mbar		**P / Pa
Run 1
*20	293.15		0.04	4
19.8	292.95		0.0463	4.63
30.0	303.15		0.0901	9.01
40.0	313.15		0.3419	34.19
50.0	323.15		1.4	140
Run 2
*20	293.15		0.03	3
19.9	293.05		0.0450	4.50
29.9	303.05		0.0859	8.59
40.4	313.55		0.2086	20.86
50.2	323.35		1.0	100
60.1	333.25		2.4	240

* - Determined by extrapolation

** - Calculated

Comment

Run 1: 6.9 g of the test substance was degassed for 64 h. Starting vacuum pressure was 0.0008 mbar. The test substance melted at approximately 40-45°C and became a viscous paste.

Run 2: 9.3 g of the test substance was placed under vacuum for 114 h. The starting pressure was 0.0008 mbar.

Conclusions:

Under the study conditions, the vapour pressure of the test substance was determined to be 4.6 Pa at 20°C.

Executive summary:

A study was conducted to determine the vapour pressure of the test substance using static method, according to EC Method A.4, in compliance with GLP. Under the study conditions, the vapour pressure of the test substance was determined to be 4.6 Pa at 20°C (Chilworth, 2017).

Description of key information

The vapour pressure of the test substance was determined experimentally using static method, according to EU Method A.4 (Chilworth, 2017) as well using QSAR model EPI Suite (US EPA, 2018).

Key value for chemical safety assessment

Vapour pressure:

4.6 Pa

at the temperature of:

20 °C

Additional information

- Experimental VP: 4.6 Pa (using static method); The study was suspected to be influenced by trapped gas/impurities.

- Weighted average QSAR based VP = 2.34E-5 Pa at 25°C (using EPI Suite v.4.11). The estimates for the major constituents are considered to be reliable with restrictions, as they do not completely fall within of the applicability domain.

Overall, based on the above information, the test substance can be considered to have low volatility potential. However, the higher VP value of 4.6 Pa has been considered further for hazard/risk assessment as a conservative approach.