Registration Dossier
Registration Dossier
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EC number: 245-122-7 | CAS number: 22613-51-0
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Link to relevant study records
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1970s-1980s
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 420 (Acute Oral Toxicity - Fixed Dose Method)
- GLP compliance:
- no
- Test type:
- fixed dose procedure
- Specific details on test material used for the study:
- AGS is administrated in a peanut oil solution
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male
- Route of administration:
- oral: gavage
- Vehicle:
- peanut oil
- Doses:
- 4830 mg/kg bw administrated in 0.01 ml (solution in peanut oil)/g bw
- No. of animals per sex per dose:
- 10
- Control animals:
- not specified
- Key result
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- > 4 830 mg/kg bw
- Based on:
- act. ingr.
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- no oral toxicity
- Executive summary:
At the concentration of 0.01 mg/g bw (Wistar male rats), the results obtained support the conclusion that AGS may be considered non-hazardous
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1970s-1980s
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 420 (Acute Oral Toxicity - Fixed Dose Method)
- Deviations:
- yes
- GLP compliance:
- no
- Test type:
- fixed dose procedure
- Specific details on test material used for the study:
- AGS is administrated in peanut oil
- Species:
- mouse
- Strain:
- Swiss
- Sex:
- male
- Route of administration:
- oral: gavage
- Vehicle:
- peanut oil
- Doses:
- 4830 mg/kg bw administrated in 0.01 ml (solution in peanut oil)/g bw
- No. of animals per sex per dose:
- 10
- Control animals:
- not specified
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- > 4 830 mg/kg bw
- Based on:
- act. ingr.
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- At the concentration of 4830 mg/kg bw (Swiss male mouse) the results obtained support the conclusion that AGS may be considered non-hazardous.
Referenceopen allclose all
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 4 830 mg/kg bw
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
