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EC number: 244-520-8 | CAS number: 21668-81-5
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-03-13 - 2017-03-16
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Version / remarks:
- OECD 103, dated 27. Jul. 1995, “Boiling Point“
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Version / remarks:
- EU-Method A.2, dated 31. May 2008, “Boiling Temperature“
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Landesamt für Umwelt, Wasserwirtschaft und Gewerbeaufsicht, Kaiser-Friedrich-Straße 7, 55116 Mainz, Germany
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- 3-[(aminoiminomethyl)thio]propanesulphonic acid
- EC Number:
- 244-520-8
- EC Name:
- 3-[(aminoiminomethyl)thio]propanesulphonic acid
- Cas Number:
- 21668-81-5
- Molecular formula:
- C4H10N2O3S2
- IUPAC Name:
- 3-(carbamimidoylsulfanyl)propane-1-sulfonic acid
- Test material form:
- solid: particulate/powder
- Details on test material:
- Storage: Room Temperature (20 ± 5°C), keep away from humidity
Constituent 1
- Specific details on test material used for the study:
- STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: The test item was stored in a tightly closed vessel at room temperature (15.8 – 22.0 °C) under dry conditions in the dark.
Results and discussion
Boiling point
- Key result
- Boiling pt.:
- 276.6 °C
- Atm. press.:
- ca. 1 013.25 mBar
- Decomposition:
- no
- Remarks on result:
- other: mean of two experiments
- Remarks:
- SD ± 0.29°C
Applicant's summary and conclusion
- Conclusions:
- The study was performed according to the OECD TG103 and EU Method A.2 (GLP) without deviations and therefore considered to be of the highest quality (reliability Klimisch 1). Differential scanning calorimetry is a scientifically reasonable method to determine not only the boiling point of a substance but also its melting point or decomposition temperature. There is no reason to believe that the results are not reliable. Two events were detected. As first event the melting point was determined with 257.28 ± 0.28 °C (530.43 ± 0.28 K), the second event is stated as the boiling point with 276.60 ± 0.29 °C (549.75 ± 0.29 K).
- Executive summary:
The boiling point was determined via DSC (differential scanning calorimetry) according to OECD 103 resp. EU A.2 under GLP.
The boiling point was determined under these circumstances as the second event with 276.60 ± 0.29 °C (549.75 ± 0.29 K)
These values are the means of two independent determinations.
The first event was indicated as melting point with 257.28 ± 0.28 °C (530.43 ± 0.28 K)
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