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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
non-GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
(27.07.95)
Deviations:
no
GLP compliance:
no
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
3-[(aminoiminomethyl)thio]propanesulphonic acid
EC Number:
244-520-8
EC Name:
3-[(aminoiminomethyl)thio]propanesulphonic acid
Cas Number:
21668-81-5
Molecular formula:
C4H10N2O3S2
IUPAC Name:
3-(carbamimidoylsulfanyl)propane-1-sulfonic acid
Test material form:
solid: particulate/powder
Details on test material:
- Name of test material (as cited in study report) : UPS ; 3-[(Amino-iminomethyl)-thio]-1-propanesulfonic acid

Results and discussion

Water solubility
Key result
Water solubility:
90 g/L
Incubation duration:
3 h
Temp.:
23 °C
Remarks on result:
other: pH not available
Details on results:
Determination of the water solubility on the basis of observation of the solution (clear solution, slightly turbid solution or turbid solution).

Applicant's summary and conclusion

Conclusions:
Water solubility = 90 g/L (soluble).
The study was performed according to OECD TG105 with deviations (no determination of pH, lacking information of individual results of the three flasks, no analytical method) and therefore reliability of Klimisch 2 has been assigned.
Executive summary:

The water solubility of the test material 3-[(aminoiminomethyl)thio]propanesulphonic acid was determined experimentally using the flask method in a non-GLP test according to OECD guideline 105. The water solubility of the test material is 90 g/L at 23 °C, the substance is soluble in water.

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