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Ecotoxicological information

Short-term toxicity to fish

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short-term toxicity to fish
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
Justification for type of information:
The target substance is hydrolytically unstable with hydrolysis half-life less than 5 minutes. The hydrolysis products have been identified to be 1-butanol and hydrated zirconium dioxide. The properties and toxiciteis of the hydrolysis products are therefore used for read-across.
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
equivalent or similar to guideline
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
not specified
Analytical monitoring:
Test organisms (species):
Pimephales promelas
Details on test organisms:
- Common name: Fathead minnow
- Source: from Environmental Research Laboratory, Duluth culture
- Age at study initiation (mean and range, SD): 33 days old
Test type:
Water media type:
Limit test:
Total exposure duration:
96 h
Key result
96 h
Dose descriptor:
Effect conc.:
ca. 1 730 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Validity criteria fulfilled:
The 96h LC50, flow through method, tested on Pimephales promelas (Fathead minnow) was 1730 mg/l. The lower value was chosen for CSA.

Description of key information

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1 730 mg/L

Additional information

No studies were conducted on the target substance, Zirconium tetrabutanolate. As the target substance hydrolyses rapidly (half-life < 5 minutes) the intrinsic properties are related to hydrolysis products of the target substance.

On the basis that if entering the environmental, this substance will quickly dissociate to form the inorganic (poorly soluble) zirconium dioxide and well-evaluated organic substances - 1 -butanol.
The zirconium dioxide is not considered further in this report as aquatic toxicity assessments do not apply.
LC50 (96h) values tested on Pimephales promelas were 1730 mg/l for1-propanol (Geiger, et al. 1984). This value was used for CSA.