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Physical & Chemical properties

Dissociation constant

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Description of key information

Dissociation constant (tetrahydrophthalic acid): pKa1 = 4.07 and pKa2 = 6.19 at 20 ± 1 °C. 

Key value for chemical safety assessment

pKa at 20°C:
4.07

Additional information

Tetrahydrophthalic anhydride rapidly hydrolyses in water to yield the corresponding acid..

The dissociation constants in water of tetrahydrophthalic acid has been investigated in accordance with OECD test methods and determined to be: pKa1=4.07 and pKa2=6.19 at 20 ± 1 °C.

The species distribution generated by the dissociation of this acid was determined, according to these constants, as function of pH.