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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Insufficient details available to make a direct reliability assessment, however, inclusion in ECHA review article coupled with official OECD guideline being followed supportive of K2 reliability score.
Reason / purpose for cross-reference:
reference to same study
Qualifier:
according to guideline
Guideline:
OECD Guideline 211 (Daphnia magna Reproduction Test)
Deviations:
no
GLP compliance:
not specified
Test organisms (species):
Daphnia magna
Test type:
semi-static
Total exposure duration:
21 d
Duration:
21 d
Dose descriptor:
EC50
Effect conc.:
> 25 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks on result:
other: The overall average of measured concentrations of the test substance in the test solutions was 90 - 99 % of nominal.
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
>= 25 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks on result:
other: The overall average of measured concentrations of the test substance in the test solutions was 90 - 99 % of nominal.
Validity criteria fulfilled:
yes
Conclusions:
The 21-day EC50 value was considered to be higher than 25 mg/L.
The 21-day NOEC value was considered to be or higher than 25 mg/L.

Description of key information

A long-term toxicity study with daphnia is available. In the study (Pawlowski, 2004) with Daphnia magna the NOEC ≥ 25 mg/L.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
25 mg/L

Additional information

A long term toxicity study with daphnia is available indicating a NOEC ≥ 25 mg/L (nominal with measured concentrations within desired ranges). The study (Pawlowski, 2004) was a semi-static 21 day study according to OECD 211.