Registration Dossier
Registration Dossier
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EC number: 215-892-9 | CAS number: 1445-45-0
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018-01-03 (experimental phase)
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Version / remarks:
- Regulation EC No. 440/2008 Method A.2. Boiling temperature
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
- Version / remarks:
- EPA OCSPP Test Guideline 830.7220 (1996) Boiling Point / Boiling Range
- Deviations:
- not specified
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
- Key result
- Boiling pt.:
- 108 - 109 °C
- Atm. press.:
- 1 013 hPa
- Conclusions:
- The Boiling point was determined in a GLP guideline study according to OECD 103 and EU method A.2 without deviations on the registered substance itself. Differential Scanning Calometry is a suitable method for boiling point determinations. Hence, there is no indication given that the results are not reliable. An endothermic effect was detected in the temperature range of 60 – 120 °C. No further thermal effects could be observed. In two different runs the boiling point was determined as 108 - 109 °C.
- Executive summary:
The boiling point / range of Trimethyl orthoacetate (TMOA) was determined in a GLP guideline study according to Regulation EC No. 440/2008 Method A.2 and OECD 103 by Differential scanning calorimetry. An endothermic effect was detected in the temperature range of 60 – 120 °C. No further thermal effects could be observed. The test item had a boiling range of 108 - 109 °Cat atmospheric pressure (1013 hPa).
Reference
Description of key information
Boiling point/range: 108 - 109 °C at atmospheric pressure (101 325 Pa) (OECD TG 103: Boiling point and EU method A.2: Boiling temperature)
Key value for chemical safety assessment
- Boiling point at 101 325 Pa:
- 108 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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