Registration Dossier

Diss Factsheets

Physical & Chemical properties

Boiling point

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018-01-03 (experimental phase)
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling Point)
Deviations:
not specified
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Version / remarks:
Regulation EC No. 440/2008 Method A.2. Boiling temperature
Deviations:
not specified
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
Version / remarks:
EPA OCSPP Test Guideline 830.7220 (1996) Boiling Point / Boiling Range
Deviations:
not specified
GLP compliance:
yes (incl. QA statement)
Type of method:
differential scanning calorimetry
Key result
Boiling pt.:
108 - 109 °C
Atm. press.:
1 013 hPa
Conclusions:
The Boiling point was determined in a GLP guideline study according to OECD 103 and EU method A.2 without deviations on the registered substance itself. Differential Scanning Calometry is a suitable method for boiling point determinations. Hence, there is no indication given that the results are not reliable. An endothermic effect was detected in the temperature range of 60 – 120 °C. No further thermal effects could be observed. In two different runs the boiling point was determined as 108 - 109 °C.
Executive summary:

The boiling point / range of Trimethyl orthoacetate (TMOA) was determined in a GLP guideline study according to Regulation EC No. 440/2008 Method A.2 and OECD 103 by Differential scanning calorimetry. An endothermic effect was detected in the temperature range of 60 – 120 °C. No further thermal effects could be observed. The test item had a boiling range of 108 - 109 °Cat atmospheric pressure (1013 hPa).

Description of key information

Boiling point/range: 108 - 109 °C at atmospheric pressure (101 325 Pa) (OECD TG 103: Boiling point and EU method A.2: Boiling temperature)

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
108 °C

Additional information

Categories Display