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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

EC50 (72h) = 61 mg/L, EC10 (72h) = 21.7 mg/L (measured, based on active matter) for Desmodesmus subspicatus (OECD 201, read across)

Key value for chemical safety assessment

EC50 for freshwater algae:
61 mg/L
EC10 or NOEC for freshwater algae:
21.7 mg/L

Additional information

In this study Hostapon SG dried was found to inhibit the growth of the freshwater green alga Desmodesmus subspicatus after 72 h. The NOEC-values for inhibition of specific growth rate and inhibition of yield after 72 h were 32.0 and 1.00 mg/L, respectively. The LOEC-values for inhibition of specific growth rate and inhibition of yield after 72 h were 100 and 3.20 mg/L, respectively. The EC50-values for inhibition of specific growth rate (ErC50) and yield (EyC50) with 95 % Confidence Intervals after 72 h were 89.9 (84.3 – 96.2) and 30.5 (21.5 – 43.4) mg/L, respectively.

All effect levels are given based on nominal concentrations of Hostapon SG dried.Values based on a.i. basis are given in the result section.

 

No studies investigating the toxicity of Disodium N-lauroyl-glutamate to algae are available. Thus, available data for the source substance Sodium N-cocoyl-glycinate was used in a read across approach. The read across is considered valid as both substances are structurally identical (solely differing in the degree of deprotonation being di- and monosodium salts, respectively), which assume very similar physico-chemical properties resulting in identical environmental behavior and ecotoxicity.

The read across key study was performed according to GLP and OECD guideline 201 using Desmodesmus subspicatus as test organism. In this study, Hostapon SG dried was found to inhibit the growth of the freshwater green alga Desmodesmus subspicatus after 72 h. The NOEC-values for inhibition of specific growth rate and inhibition of yield after 72 h were 32.0 and 1.00 mg/L, respectively. The LOEC-values for inhibition of specific growth rate and inhibition of yield after 72 h were 100 and 3.20 mg/L, respectively. The EC50-values for inhibition of specific growth rate (ErC50) and yield (EyC50) with 95 % Confidence Intervals after 72 h were 89.9 (84.3 – 96.2) and 30.5 (21.5 – 43.4) mg/L, respectively.

All effect levels are given based on nominal concentrations of Hostapon SG dried.Values based on a.i. basis are given in the result section.