Registration Dossier
Registration Dossier
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EC number: 231-397-0 | CAS number: 7531-52-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 7.9.2001-11.10.2001
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- (S)-pyrrolidine-2-carboxamide
- EC Number:
- 231-397-0
- EC Name:
- (S)-pyrrolidine-2-carboxamide
- Cas Number:
- 7531-52-4
- Molecular formula:
- C5H10N2O
- IUPAC Name:
- (S)-pyrrolidine-2-carboxamide
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 72 h
Test conditions
- Reference substance (positive control):
- yes
- Remarks:
- kalium dichromate
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Results with reference substance (positive control):
- EbC50 (72 h) = 0.64 mg/L
ErC50 (72 h) = 1.5 mg/L
Applicant's summary and conclusion
- Conclusions:
- According to the classification criteria described in REGULATION (EC) No 1272/2008 (CLP) the product has not to be classified.
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