Registration Dossier
Registration Dossier
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EC number: 202-941-4 | CAS number: 101-42-8
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: "Wasseruntersuchungen" TGL 28 400
- Deviations:
- not specified
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- yes
- Remarks:
- Fish longer (7-10 cm), Temperature 20°C
- GLP compliance:
- no
- Analytical monitoring:
- not specified
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- TEST ORGANISM
- Common name: Rainbow trout
- Length at study initiation (mean and range, SD): 7 to 10 cm - Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
- Hardness:
- 0.5 to 1.0 mmol/L
- Test temperature:
- 20°C
- Details on test conditions:
- TEST SYSTEM
- Material, size, headspace, fill volume: fill volume 20 L
- Aeration: yes - Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 204 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Conclusions:
- 96 h-LC50 rainbow trout: 204 mg/L
- Executive summary:
In the publication from Tscheu-Schlüter and Skibba (1986) the acute toxicity of Fenuron (90% purity) was determined on rainbow trout. After 96 hours, the LC50 was 204 mg/L. In deviation to the most recent OECD 203 guideline the test temperature was 20°C and the fish length was 7 -10 cm. These deviations were considered to be acceptable as it is not expected that these parameters will change the result for orders of magnitude.
The result is considered to be relevant and reliable with restrictions for the risk assessment.
Reference
Description of key information
Data from four freshwater fish are available. The most reliable study with rainbow trout resulted in an LC50 of 204 mg/L. The data demonstrate that fish are less sensitive when compared to algae. Hence further testing was considered not necessary.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 204 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
