Registration Dossier

Physical & Chemical properties

Melting point / freezing point

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2003-04-04 to 2003-07-28
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
1993
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
thermal analysis
Key result
Melting / freezing pt.:
-23 °C
Decomposition:
no
Sublimation:
no
Remarks on result:
other: +/- 1 °C

'Melting plateaus' were observed for acetonitrile at -44 °C for both duplicate runs, which was slightly lower than the reported MP of -45 °C (Merck, 1976). It was visually observed that approx. half of the CH3CN in the tubes had melted at the plateau temperature of -44 °C. Therefore, melting point results for the Test Substance were corrected for a bias of 1 °C.

`Melting plateaus' were observed for the test item. The inflection points were at approx. -22 °C for both duplicate runs. Therefore, the reported MP of the test item, adjusted for the bias mentioned above, was -23 °C. At this temperature, it was observed that approx. half of the test item in the tubes had melted. Duplicate runs for both the Reference Substance (CH 3CN) and the test item indicated that the experimental error was approx. 1 °C.

Conclusions:
Melting point (OECD 102 - thermal analysis): -23 °C (+/- 1 °C)
Executive summary:

In a study performed according to OECD 102 compliant with GLP, the melting point (MP) was determined by freezing a 20-mL sample of the test item in a test tube and electronically recording the temperature of the sample as it warmed (in duplicate). The apparatus was calibrated using acetonitrile.

The observed melting point of the test substance 3-chloro-o-xylene, was -23 ± 1 °C.

Description of key information

Melting point (OECD 102 - thermal analysis): -23 °C (+/- 1 °C)

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
-23 °C

Additional information

In a study performed according to OECD 102 compliant with GLP, the melting point (MP) was determined by freezing a 20-mL sample of the test item in a test tube and electronically recording the temperature of the sample as it warmed (in duplicate). The apparatus was calibrated using acetonitrile.

The observed melting point of the test substance 3-chloro-o-xylene, was -23 ± 1 °C.