Registration Dossier

Physical & Chemical properties

Melting point / freezing point

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Principles of method if other than guideline:
No method detailed
GLP compliance:
no
Type of method:
other: Not detailed
Key result
Melting / freezing pt.:
230 - 232 °C
Conclusions:
The melting point of gallic acid is 230-232°C.
Executive summary:

The melting point of gallic acid is 230-232°C.

Endpoint:
melting point/freezing point
Type of information:
other: Handbook
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Principles of method if other than guideline:
No method detailed
GLP compliance:
no
Type of method:
other: not detailed
Key result
Melting / freezing pt.:
253 °C
Conclusions:
The melting point of gallic acid is 253°C.
Executive summary:

The melting point of gallic acid is 253°C.

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Principles of method if other than guideline:
No method detailed
GLP compliance:
no
Type of method:
other: not detailed
Key result
Melting / freezing pt.:
235 - 238 °C
Conclusions:
The melting point of gallic acid is 235-238°C.
Executive summary:

The melting point of gallic acid is 235-238°C.

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Principles of method if other than guideline:
No method detailed
GLP compliance:
no
Type of method:
other: not detailed
Key result
Melting / freezing pt.:
254 - 256 °C
Conclusions:
The melting point of Gallic acid is 254-256 °C.
Executive summary:

The melting point of Gallic acid is 254-256 °C.

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
GLP compliance:
no
Type of method:
differential scanning calorimetry
Key result
Decomposition:
yes
Decomp. temp.:
>= 210 - <= 431 °C
Remarks on result:
not determinable
Remarks:
decomposition of the test item occurs together with melting

The test item is stable up to 74°C when occurs the first mass loss (9.1%) up to 107°C due to dehydration (endothermic peak at 92°C) that correspond to one mol. Above this temperature until 210°C the test item is stable with no mass loss and no endo or exothermal events. The second mass loss (78.8%) occurs between 210-264°C with an endothermic peak (256°C) observed in the DTA curve. Immediately occurs the third mass loss (10.5%) with the oxidation of the organic matter and two corresponding exothermic peaks (at 410 and 431°C), respectively. The final residue of decomposition of the test item was 1.6% of the total initial mass (carbon residue). The melting point was not determined because the it occurs together the second mass loss (between 210-264°C).

No boiling was observed up to 431°C.

Conclusions:
No melting point was determined as it occured together with decomposition of the test item, starting at 210°C. No boiling was observed up to 431°C.
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Qualifier:
no guideline followed
Principles of method if other than guideline:
no information but peer-reviewed handbook
GLP compliance:
not specified
Type of method:
other: not specified
Key result
Sublimation:
yes
Subl. temp.:
>= 210 °C
Remarks on result:
other:
Remarks:
see below

Sublimes at 210°C, giving a stable form with melting point 258 to 265°C and an unstable form with melting point 225 to 230°C.

Conclusions:
Litterature reports that gallic acid sublimes at 210°C, giving a stable form with melting point 258 to 265°C and an unstable form with melting point 225 to 230°C.
However the method is unknown.

Description of key information

The weight of evidence approach may apply as 6 independent sources of information are available:

A) Zhang et al., 2004       

Melting point of gallic acid: 254-256°C

B) Imran et al., 2009      

Melting point of gallic acid: 235-238°C

C) Cai & Wu, 1996       

Melting point of gallic acid: 230-232°C

D) CRC Handbook, 1971

Melting point of gallic acid: 253°C

E) Alberti et al., 2016

No melting point was determined as it occured together with decomposition of the test item, starting at 210°C. No boiling was observed up to 431°C.

F) Budavari (1996)

Litterature reports that gallic acid sublimes at 210°C, giving a stable form with melting point 258 to 265°C and an unstable form with melting point 225 to 230°C.

However the method is unknown.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
225 °C

Additional information

A range of melting point of gallic acid of 225 -256°C is provided in 4 independent sources of information.

However, litterature reports that gallic acid can sublime and/or decompose from 210°C.