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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

In the key study, propane-1-thiol reached 17 % biodegradation in 28 days and therefore cannot be considered readily biodegradable under the strict conditions of OECD guideline 301D.

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information

Micro-organisms from a predominantly domestic sewage treatment plant were exposed to 1 mg/L propane-1-thiol for 28 days in dark glass closed biological oxygen demand bottles (Harlan, 2012). Propane-1-thiol reached 17 % biodegradation in 28 days and therefore cannot be considered readily biodegradable under the strict conditions of OECD guideline 301D. The toxicity control showed that propane-1-thiol is not inhibitory to micro-organisms at a concentration of 1 mg/L.

Only the summary of Thiebaud (1997) is available and therefore it cannot be fully evaluated. However, this summary indicated that propane-1-thiol reached 84.7% biodegradation after 28 days, indicating that it is readily biodegradable and that it is not inhibitory to microorganisms. This is a non-GLP study following OECD guideline 301D. There are limitations in reporting, but the study is considered Klimisch 2 (reliable with restrictions) and suitable for use as a supporting study for this endpoint.