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Melting point / freezing point

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melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
equivalent or similar to guideline
OECD Guideline 102 (Melting point / Melting Range)
GLP compliance:
not specified
Type of method:
capillary method
Specific details on test material used for the study:
- Purity test date: production grade TGS (PG), purified TGS (P) and TGS containing niacinamide TGS (N)
Key result
Decomp. temp.:
ca. 114.5 °C
Remarks on result:
other: heating of 1°C per minute
Decomp. temp.:
125.5 °C
Remarks on result:
other: heating of 5°C per minute
Decomposition of the test substance was observed using a Capillary tube in a metal block at temperatures at 114.5°C at a heating rate of 1°C per minute. Melting of the test substance was not observed below the temperature at which decomposition started. Based on this, the test substance has no melting temperature.
Executive summary:

On heating, TGS starts to decompose before its melting point. The temperature at which three grades of TGS convert from a decomposing solid phase to a decomposing liquid phase has been measured. The melting points of production grade the test substance, when heated from 10°C below their melting points at an approximate average rate of heating of 1°C per minute and corrected using National Physical Laboratory Chemical Reference Materials for the calibration of melting point apparatus are: 114.5 °C; at an approximate average rate of heating of 5°C per minute and the appropriate correction: 125.5 °C.

Description of key information

The melting point of the test substance was determined similar to OECD Guidelines for the Testing of Chemicals no. 102: "Melting Point / Melting Range" (July 27, 1995).

The decomposition temperature was determined to be 114.5°C.

Key value for chemical safety assessment

Additional information