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Environmental fate & pathways

Adsorption / desorption

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Reference
Endpoint:
adsorption / desorption: screening
Type of information:
other: Theoretical Statement
Adequacy of study:
key study
Study period:
27 September 2017 - 19 October 2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Qualifier:
according to guideline
Guideline:
OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC estimation method
Radiolabelling:
not specified
Details on study design: HPLC method:
Not applicable. A study on the adsorption coefficient (Koc) on soil and on sewage sludge cannot be performed using High Performance Liquid Chromatography (HPLC) method as described in OECD guideline 121 for an inorganic substance or mineral salt test item such as dilithium tetraborate.
Details on sampling:
Not applicable.
Details on matrix:
Not applicable.
Details on test conditions:
Not applicable.
Key result
Sample No.:
#1
Remarks on result:
not measured/tested
Details on results (HPLC method):
In accordance with the REACH Regulation, the study on the adsorption coefficient (Koc) on soil and on sewage sludge cannot be performed using High Performance Liquid Chromatography (HPLC) method as described in OECD guideline 121 for an inorganic substance or mineral salt test item such as dilithium tetraborate.
Validity criteria fulfilled:
not applicable
Conclusions:
In accordance with the REACH Regulation, the study on the adsorption coefficient (Koc) on soil and on sewage sludge cannot be performed using High Performance Liquid Chromatography (HPLC) method as described in OECD guideline 121 for an inorganic substance or mineral salt test item such as dilithium tetraborate.
Executive summary:

It was proposed to investigate the adsorption/desorption potential of the test substance using OECD 121. In accordance with the REACH Regulation, the study on the adsorption coefficient (Koc) on soil and on sewage sludge cannot be performed using High Performance Liquid Chromatography (HPLC) method for an inorganic substance or mineral salt test item such as dilithium tetraborate.  A statement was therefore prepared by the laboratory to this effect.

Description of key information

In accordance with the REACH Regulation, the study on the adsorption coefficient (Koc) on soil and on sewage sludge cannot be performed using High Performance Liquid Chromatography (HPLC) method as described in OECD guideline 121 for an inorganic substance or mineral salt test item such as dilithium tetraborate.  

Key value for chemical safety assessment

Additional information