Reaction mass of calcium 2,6-bis(3-carboxylatopropanamido)hexanoate and isomers of calcium amino-(3-carboxylatopropanamido)hexanoate

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.1 mg/L

Assessment factor:

1 000

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

1 mg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0.01 mg/L

Assessment factor:

10 000

Extrapolation method:

assessment factor

PNEC marine water (intermittent releases):

1 mg/L

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

100 mg/L

Assessment factor:

10

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

0.362 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

0.036 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

0.014 mg/kg soil dw

Extrapolation method:

equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential for bioaccumulation

Additional information

PNEC (freshwater sediment):

K(susp-water) = 0.905 m³/m³

RHO_(susp) = 1150

Conversion factor (wwt -> dwt): 4.6

PNEC_freshwater sediment = (Ksusp-water) / RHOsusp) * PNEC (freshwater) * 1000

= (0.905/1150) * 0.1 * 1000

= 0.0787 mg/kg wwt

= 0.362 mg/kg dwt

The PNEC (freshwater sediment) of dry weight (dw) is 0.362 mg/kg corresponding to the wet weight (ww) value of 0.0787 mg/kg (conversion factor: 4.6).

PNEC (marine sediment):

K(susp-water) = 0.905 m³/m³

RHO_(susp) = 1150

Conversion factor (wwt -> dwt): 4.6

PNEC_freshwater sediment = (Ksusp-water) / RHOsusp) * PNEC (marine water) * 1000

= (0.905/1150) * 0.01 * 1000

= 0.0079 mg/kg wwt

= 0.0362 mg/kg dwt

The PNEC (marine water - sediment) of dry weight (dw) is 0.0362 mg/kg corresponding to the wet weight (ww) value of 0.0079 mg/kg (conversion factor: 4.6).

PNEC soil:

K(soil-water) = 0.206 m³/m³

RHO(soil) = 1700

Conversion factor (wwt -> dwt): 1.13

PNEC_soil

= (K(soil-water) / RHOsoil) * PNEC (freshwater) * 1000

= (0.206/1700) * 0.1 * 1000

= 0.0121 mg/kg wwt

= 0.0137 mg/kg dwt

The PNEC (soil) of dry weight (dw) is 0.0137 mg/kg corresponding to the wet weight (ww) value of 0.0121 mg/kg (conversion factor: 1.13).

Conclusion on classification

Aquatic acute toxicity

48 h, EC50 (Daphnia magna): >100 mg/L (nominal)

72 h, ErC50 (Raphidocelis subcapitata) >100 mg/L (nominal)

96 h, LC50 (Danio rerio): >100.0 mg/L (nominal)

 

Aquatic chronic toxicity

72 h, ErC10 (Raphidocelis subcapitata): 26.79 mg/L (nominal)

 

Biodegradation: Inherently biodegradable: 48.6 % after 28 days (OECD 301D)

 

Classification according to CLP

Based on the data above, the substance has not to be classified for short-term (acute) or long-term (chronic) toxicity according to the 17th ATP of the Regulation (EC) No 1272/2008 (CLP).