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EC number: 263-193-2 | CAS number: 61791-59-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
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- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
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- Additional physico-chemical information
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- Endpoint summary
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- Environmental data
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- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
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- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
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- Genetic toxicity
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- Specific investigations
- Exposure related observations in humans
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- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
The target substance Glycine, N-methyl-, N-coco acyl derivatives, sodium salts (CAS 61791-59-1) has a low potential for bioaccumulation at environmentally relevant pH based on its physico-chemical properties, including a log Kow of -1.3 (23 °C, OECD 117) and a log D (used for ionisable substances instead of log Kow) of 0.61 to 2.40 at pH 7 and of -0.30 to 1.53 at pH 9 (SPARC v4.6). According to REACh regulation (EC) No 1907/2006, substances with log Kow ≤ 3.0 have a low potential for bioaccumulation. Thus, further testing is not required in accordance with Annex IX, column 2, 9.3.2. of Regulation (EC) No. 1907/2006.
Furthermore, predicted BCF values also indicate that the potential for bioconcentration in aquatic organisms is low. The estimated BCF values are 3.16 L/kg wet-wt (BCFBAF model v3.01 regression-based), 0.89 L/kg wet-wt (BCFBAF model v3.01 Arnot-Gobas, including biotransformation upper trophic) and 3.0 – 74.0 L/kg wet-wt (VEGA v1.2.3, CAESAR, Meylan and KNN models), which are clearly below the cut-off values of 2000 L/kg wet-wt for bioaccumulative and 5000 L/kg wet-wt for very bioaccumulative substances, as laid down by section 1 of Annex XIII of REACH Regulation (EC) No 1907/2006. In addition, toxicokinetic considerations with regard to absorption, distribution, metabolisation and excretion of the substance provide further evidence for a low potential for bioaccumulation.
In conclusion, the potential for bioaccumulation is expected to be low for Glycine, N-methyl-, N-coco acyl derivatives, sodium salts (CAS 61791-59-1).
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