Potassium 2-(4-chloro-2-methylphenoxy)propionate

Partition coefficient

Administrative data

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Study period:

17.10.2005 - 26.10.2005

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2005

Report date:

2005

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method A.8 (Partition Coefficient - Shake Flask Method)

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Partition coefficient type:

octanol-water

Test material

Test material information

Constituent 1

Reference substance name:

Mecoprop

EC Number:

230-386-8

EC Name:

Mecoprop

Cas Number:

7085-19-0

Molecular formula:

C10H11ClO3

IUPAC Name:

2-(4-chloro-2-methylphenoxy)propanoic acid

impurity 1

Reference substance name:

Water

EC Number:

231-791-2

EC Name:

Water

Cas Number:

7732-18-5

Molecular formula:

H2O

IUPAC Name:

water

Test material form:

solid

Results and discussion

Partition coefficient

Partition coefficient 1

Key result

Type:

log Pow

Partition coefficient:

>= 2.53 - <= 2.65

Temp.:

20 °C

pH:

4

Partition coefficient 2

Key result

Type:

log Pow

Partition coefficient:

>= 0.03 - < 0.05

Temp.:

20 °C

pH:

7

Partition coefficient 3

Key result

Type:

log Pow

Partition coefficient:

>= -1 - <= -0.98

Temp.:

20 °C

pH:

9

Applicant's summary and conclusion

Conclusions:

The partition coefficient for in octanol: at 20 °C was for mecoprop acid was determined to be:
2.59 ± 0.06 at pH 4.0
0.04 ± 0.01 at pH 7.0
0.99 ± 0.01 at pH 9.0